The Mercedes S-Class is a benchmark for limousines: each generation introduces solutions that later find their way into lower segments. From the "armored" W140 through the lighter W220, the technological W221, and finally the digital W222 – the core remains the same: comfort, quietness, and confident driving. With each iteration, the materials, electronics, and assistance systems have evolved, impacting the list of parts that are worth knowing in practice. Users ask not only about engines and transmissions, but also about suspension, comfort features, and body modules – and here, well-matched Mercedes parts from the same model year family shorten assembly time. Below, we summarize the most recognizable differences between the W140, W220, W221, and W222, and identify typical components that truly improve the everyday driving experience. The text also includes interesting information about the model (e.g. " Mercedes W140 420 ", " Mercedes CL 420 W140 ") and definitions useful in conversation with a workshop or in a shop.
Mercedes S-Class W140 – the "last battleship" and the mechanics that build the legend
The first two things associated with the W140 are solidity and acoustic silence, achieved through thick glass, extensive soundproofing, and a massive structure. In the V8 variants (e.g., the Mercedes W140 420 and in the Mercedes CL 420 W140 coupé ), the stability of the cooling system and durability of the accessories were key, while in the diesels, refinement at high mileage were key. The original hinges, soft-close locks, central locking vacuum pumps, and interior components still "do the job" today, and as used OEM parts, they help maintain the car's consistent character. The W140 readily accepts complete door harnesses, window motors, and seat adjustment panels from the same family – they mechanically fit and allow the electronics to breathe. On the driving side, it pays to check the bushings, stabilizer links, and hubs – details that contribute to the "on-rails" feeling in this large sedan.
Mercedes S W140 – parts that are usually worth looking for as original used ones
The most frequently chosen components include: lock and soft-close actuators, complete window mechanisms, seat and mirror control modules, carpet and rug kits, and upholstery components. In mechanical systems, steering knuckles, hubs, and good control arms are good candidates – when properly installed, they restore steering linearity. In cooling systems, tanks and hoses in good condition are popular, as original fittings and diameters eliminate improvisation. Axle bushing kits are widely used in suspension systems – replaced in pairs and "per axle" for the best results. 
Mercedes S-Class W220 – lightness, electronics and the first wave of "digital"
The W220 introduced weight reduction and a softer, "luxurious" aesthetic, while significantly expanding the range of comfort and safety electronics. This is where extensive body modules, active seats and control panels became common, which, over the years, require cleaning of connectors and replacement of communication elements. In practice, maintenance projects focus on the suspension ( bushings, hubs, stabilizers), the braking system ( discs + pads of appropriate specifications) and interior elements that "rejuvenate" the cabin. The W220 responds to good hubs and bearings with the correct tightening torque – this restores silence and stability on longer journeys. On the comfort side, complete sets of door harnesses, as well as window switches and motors, are replaced; using sets from the same batch saves time and the risk of "Christmas tree damage."
Mercedes S W220 – details that make a difference in everyday impression
When replacing upholstery and panel elements, it's worth sticking to the year indexes, as the clips and guides changed subtly. The "comfort package" includes heating mats, actuators, and seat occupancy sensors – a complete set from a single donor significantly speeds up the work. The correct rear axle bushings and fresh shock absorber mounts are noticeable during daytime driving; the car stops rocking and "slaps" less over lateral irregularities. When it comes to the braking system, ensuring the geometry after installation and proper bleeding significantly shortens the braking distance and stabilizes the directional stability.
Mercedes S-Class W221 – elegant "business class" and a leap in assistance systems
The W221 entered the era of mature assistants, better infotainment, and a more precise chassis, maintaining a "damped" comfort at high speeds. In this generation, users often look for complete sets of seats, steering wheels, and center consoles, as they are the ones that "refresh" the car's perception. Mechanically, the most effective are packaged replacements of bushings and shock absorber mounting elements and wheel bearings; sounds and micro-vibrations begin to disappear from the first kilometer. In assistance systems, sensors and wiring harnesses are replaced in sets to avoid software version conflicts – a practice that shortens diagnostics. The W221 responds well to a thorough steering rack service and efficient power steering; the heavier front end with additional modules favors precision in this area.
Mercedes S W221 – what the second-hand market chooses
The most frequently replaced items include newer steering wheels, panels and buttons with wiring harnesses, seat sets, headlights with complete mountings, and steering knuckles/bearings. On the comfort side, new drive mounts and rear axle bushings quickly improve the experience. In electrical systems, it's wise to select modules in "families," as mixing versions generates unnecessary diagnostic visits. The final step is a minor aesthetic: moldings and door handles – the originals fit right away, without experimentation. 
Mercedes S-Class W222 – a digital limousine with an emphasis on UX and silence
The W222 focused on digital integration, a quieter cabin, and even better isolation of passengers from the outside world, while maintaining stability on long journeys. The most sought-after components are multimedia components, control panels, lamps, seats, and wiring harnesses – single-source kits minimize variations between versions. The "chassis package" makes a significant difference in daytime driving: elastokinematic bushings, axle bearings, and shock absorber mounts, as they contribute to precision and quietness. In the drivetrain, the driveshafts and differential seals are particularly noteworthy – replaced during service, they eliminate long-distance growl. In the long-wheelbase (L) variants, proper wiring harness routing in the doors and headliners eliminates the most common minor comfort issues.
Mercedes S W222 – used parts that make your car look younger
In practice, the first thing you'll want to do is replace the seats or steering wheel, as these are the quickest to feel in your hands and back. The second step involves replacing the lamps with complete mounts and wiring harnesses – a plug-in within the family makes it easier to activate the functions. In the driving elements, a real leap forward is felt thanks to the new elastokinematics and wheel bearings; the cabin becomes even more relaxed. If infotainment is on the list, start with a complete "single-year" kit, as mixing versions is the most common source of surprises.
Mercedes S – interesting facts and phrases that users are looking for
In search engines, " Mercedes W140" appears " next to " Mercedes W222 " – users compare the "armor" of the past with the "digital" of today and ask about maintenance costs. The thread " Mercedes S85 " is sometimes confused with engine codes and body versions, so it's worth specifying the year or VIN in the conversation, but it's not necessary to use this phrase every time. The phrases "Mercedes W140 420" and "Mercedes CL 420 W140" are also popular, as they are basic reference points for collectors and classic car enthusiasts. Users ask about "Mercedes parts" at the detailed level: steering knuckles, hubs, wiring harnesses, panels, modules, and full interior kits. On the shopping list, the package approach wins: less disassembly, one appointment, and one geometry.
TABLE – Mercedes S-Class: generations, features, where they "make a difference"
| Generation | Years | Distinctive feature | Used Mercedes parts that are usually worth it |
|---|---|---|---|
| W140 | 1991–1998 | "armor", silence | window/soft-close mechanisms, seat modules, steering knuckles/hubs |
| W220 | 1998–2005 | lighter body, more comfort | door harnesses, window switches, axle bushings/bearings |
| W221 | 2005–2013 | assistants, more mature infotainment | seats/steering wheels, lamps with mountings, modules in sets |
| W222 | 2013–2020 | digital UX, even quieter | infotainment panels and kits, harnesses, elastokinematics/bearings |
TABLE – Mercedes S: Quick Design Tips
| Step | What do you usually do first? | Why |
|---|---|---|
| 1 | seats/steering wheel/touch elements | the ergonomics and "touch" of the car work every day |
| 2 | bushings/bearings/shock absorber mounts | stability, silence, no micro-vibrations |
| 3 | bundles and modules in "families" | fewer version conflicts and "Christmas trees" |
| 4 | lamps with complete handles | plug-in, consistent homologation |
| 5 | visual elements and interior details | quick "rejuvenation" effect without any modifications |
FAQ – Mercedes S-Class: W140 → W222 (frequently asked questions)
| Question | Short answer |
|---|---|
| How does the W140 differ from the W222 in everyday driving? | The W140 is "mechanical" solidity and soundproofing, the W222 - digital UX and even greater silence. |
| What parts used give the fastest results? | Seats, steering wheel, lamps with mounts and axle bushing/bearing package. |
| Does it make sense to mix bundles and modules between years? | Only within one family; a complete set from one donor simplifies diagnosis. |
| What to watch out for when driving high mileage? | Elastokinematics, bearings, differential seals and exhaust system silence. |
| Is it worth looking for "car for parts" for W140/W220? | Yes – interiors and window/soft-close mechanisms are easiest to find in a set. |
| How to combine work so as not to return to geometry? | Suspension and wheels in one piece; modules and harnesses in sets. |
| New vs used – what is better? | Used OEM provides predictable fitment and maintains the look and feel, often at a lower overall cost. |
